You’ve probably been warned that if you don’t finish that course of antibiotics, you could wind up battling antibiotic-resistant bacteria. But a growing body of research suggests that the opposite might be true. What does this mean for you and your next sinus infection? Flora talks with antimicrobial resistance expert Amy Mathers to find out.Plus, the driver of fibromyalgia, a condition that can cause debilitating chronic pain and brain fog, has been something of a mystery. Patients’ imaging and blood work often turn up normal, and many have felt dismissed by doctors.A recent large-scale study identified a group of genes associated with the disease, a breakthrough that may help doctors understand people’s risk of developing the condition and reveal something about the nature of this mysterious illness. Flora talks with Nasa Sinnott-Armstrong, one of the study’s lead authors.Guests:Dr. Amy Mathers is medical director of antimicrobial stewardship and an associate professor of medicine and pathology at the University of Virginia School of Medicine.Dr. Nasa Sinnott-Armstrong is an assistant professor of computational biology and public health at Fred Hutch Cancer Center in Washington state.Transcript will be available after the show airs on sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that’s keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

When states began legalizing recreational cannabis a couple decades ago, 25 million Americans said they used the drug. That number nearly tripled to 70 million by 2023.There are a lot of open questions about how it affects us. Why do some people find more pain relief from THC than traditional painkillers? Is it really better for sleep? What are the effects of long-term use?Host Flora Lichtman is joined by two scientists taking on these kinds of questions: Experimental psychologist Ryan Vandrey, who’s studied the health effects of cannabis for 26 years, and neuropsychologist Natasha Wade, who studies the effects of substance abuse on adolescent brains. She recently analyzed data from 11,000 teens to understand how cannabis affects development.Guests:Dr. Ryan Vandrey is an experimental psychologist and professor at the Johns Hopkins University Behavioral Pharmacology Research Unit and helps lead the Johns Hopkins Cannabis Science Lab.Dr. Natasha Wade is an associate professor in the Department of Psychiatry at UC San Diego and licensed clinical neuropsychologist.Transcript will be available after the show airs on sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that’s keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

There’s a flashy new find in the hunt for dark matter—the stuff that makes up 85% of all matter in the universe, but we have no clue what it is.A mile under Lead, South Dakota, is a giant cauldron filled with 7 tons of liquid xenon, encased in water and surrounded by super-sensitive photodetectors. Known as the LZ detector, its job is to look for flashes of light that come from particles bumping into xenon atoms. And during its observations, the researchers saw a very weird flash—a bump that doesn’t look like it came from any particle we know of.Flora talks with physicist Richard Gaitskell about the hunt for a dark matter particle and why he’s excited about this weird little finding. Guest:Dr. Richard Jeremy Gaitskell is a physicist at Brown University and a leading scientist in the search for particle dark matter. He is a co-founder of the Large Underground Xenon experiment.Transcript will be available after the show airs on sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that’s keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Once upon a time, much of what we call “science” was performed by people called “natural philosophers,” delving into mysteries of nature, physics, chemistry, and more. Physicist and author Carlo Rovelli argues that there’s still a great need for philosophy, and that the two fields can and should learn from each other in investigating reality. Rovelli joins Host Ira Flatow to talk about big ideas in physics, and his new book, “On The Equality of All Things: Lessons on Physics and Philosophy.”Read an excerpt from “On The Equality of All Things.”Guest:Dr. Carlo Rovelli is an Italian theoretical physicist and the author of “On The Equality of Things.”Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that’s keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Between E. coli in blueberries, glass in popsicles, and that dreaded cyclospora, this summer was all about keeping a wary eye on the groceries in the fridge. But how does the recall data stack up against previous years? And are federal cuts to food safety agencies to blame? Flora talks to food safety expert Brian Ronholm to get the big picture.Plus, more than 1.5 million cars have been recalled this year for risk of bursting into flames. As automotive journalist Jason Torchinsky explains, it's a miracle it doesn’t happen more often.Guests:Brian Ronholm is the director of food policy at Consumer Reports.Jason Torchinsky is an automotive journalist and co-founder of Autopian.Transcript will be available after the show airs on sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that’s keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

On social media, the vagus nerve often gets billed as the gateway to nervous system nirvana: It’s your ticket to better rest, relaxation, and health if you “stimulate” it correctly. Where did this idea come from, and what does the research say?In March, Host Flora Lichtman talked with neurosurgeon Kevin Tracey, a pioneer of a field called bioelectronic medicine, which uses techniques to stimulate the nervous system with electricity. Back in the 1990s, he was the first to discover that the vagus nerve regulates the immune system and inflammation.Guest:Dr. Kevin Tracey is a neurosurgeon, and president and CEO of the Feinstein Institutes for Medical Research at Northwell Health. He is the author of The Great Nerve.Transcript will be available after the show airs on sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that’s keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Much of the code that describes the inner workings of social networks, helps apps predict your musical interests, and underlies innovations in AI traces back to advances in mathematical theory and data science that fundamentally describe how massive networks behave.Jennifer Chayes helped create that field of math. She also spent 20 years at Microsoft building interdisciplinary research labs. Now, at UC Berkeley, her interests lie in using machine learning to work on topics like materials science, cancer immunotherapy, ethical decision-making, and climate change. She joins Flora for a wide-ranging discussion about math, networks, AI, academia, and her path between them. Guest:Dr. Jennifer Chayes is the dean of the College of Computing, Data Science, and Society at UC Berkeley.Transcript will be available after the show airs on sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that’s keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

A new mRNA vaccine for melanoma is making headlines. Moderna and Merck recently announced results from their clinical trial suggesting that this new vaccine, in combination with the cancer drug Keytruda, reduced recurrence rates in patients. The companies have not yet released full data from the trial. So, how does the vaccine work? And does this mark the beginning of a new era of cancer treatments using mRNA vaccine technology? Ira talks with physician Michael Postow, whose patients were part of the drug trial at Memorial Sloan Kettering Cancer Center. Guest: Dr. Michael Postow is chief of the melanoma service at Memorial Sloan Kettering Cancer Center. Transcript will be available after the show airs on sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that’s keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

When you see a mushroom popping up from the forest floor, that mushroom is just the tip of the fungal iceberg for a vast world beneath the surface. But the nature of fungal life makes it hard to answer some basic questions. What exactly does it mean to be one individual organism? And how do you tell how old a fungus is, when parts of it can recycle, regenerate, and grow again? Flora talks with fungal researcher Kristin Aleklett about the challenge of fungal age, and how researchers are trying to better understand what fungi are doing in the world under the ground. Guest: Dr. Kristin Aleklett is a researcher at Lund University in Sweden. Transcript will be available after the show airs on sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that’s keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

There’s been wave after wave of bad news about the ocean: warming temperatures, overfishing, acidification, coral bleaching. But in the last few years, there have also been some big wins for the big blue—as well as a narrative shift, in which the ocean itself has almost become its own larger-than-life character in conservation conversations. So how should we think about the future of the seas? And how do the stories we tell about the ocean shape how we think about it? Flora chats with marine biologist Helen Scales, author of “What the Wild Sea Can Be,” which is the Science Friday book club pick for September and October. Check out the SciFri Book Club to read along. Read an excerpt from “What the Wild Sea Can Be: The Future of the World’s Ocean.” Guest: Dr. Helen Scales is a marine biologist and author of several books, including “What the Wild Sea Can Be: The Future of the World’s Ocean.” Transcript will be available after the show airs on sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that’s keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.